[Cardiologist Douglas] Losordo bemoans the broad-based assault by ESC researchers and the media to exaggerate the potential of ESC research while downplaying or even ignoring tremendous breakthroughs in ASC work. "I don't have any personal religious or other objections to ESC research despite the vowels in my name," he says, referring to his Italian Catholic heritage. "But as a clinical investigator I have an obligation to develop therapies which appear to be of most use to my patients."